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Buy Ecstasy Online (also known as 3,4-Methylenedioxymethamphetamine, E, XTC, molly, mandy, and MDMA) is an entactogen substance of the amphetamine class. MDMA is considered to be the prototype entactogen and is part of a group that includes substances like MDA, methylone, and 6-APB. It acts primarily by increasing the activity of neurotransmitters serotonin, dopamine, and norepinephrine in the brain.
MDMA was first synthesized in 1912. It first saw use in underground psychotherapy circles in the 1970s. In the 1980s, MDMA spread into nightlife and rave culture and was subsequently banned. In 2014, MDMA was estimated to be one of the most popular recreational drugs used in the world, alongside cocaine and cannabis.Researchers are investigating whether MDMA may assist in treatment-resistant posttraumatic stress disorder (PTSD), social anxiety in autistic adults, and anxiety in those with life-threatening illness.
Typical effects of MDMA include anxiety relief, disinhibition, enhanced empathy and sociability, relaxation, and euphoria. MDMA is classified as an entactogen due to how it facilitates feelings of closeness with oneself and others. It is commonly associated with dance parties, raves, and electronic dance music. Tolerance to MDMA builds unusually quickly and many users report that it dramatically loses its effectiveness if used on a regular basis. It is commonly recommended to wait one to three months between uses to give the brain enough time to restore serotonin levels.
Acute adverse effects of Buy Ecstasy Online are usually the result of high or multiple doses, although single dose toxicity can occur in susceptible individuals. The most serious short-term physical health risks of MDMA are overheating and dehydration, which has resulted in deaths. MDMA has also been shown to be neurotoxic at high doses. However, it is unclear if this risk applies to typical users. It is highly advised to use harm reduction practices if using this substance.
History and culture
MDMA was originally synthesized in 1912 by the Merck chemist Anton Köllisch. Köllisch was interested in developing substances that would help manage excess bleeding and was interested in the activity of MDMA, an intermediary in the production of hydrastinine, a hemostatic agent used at the time. In 1965, Alexander Shulgin synthesized MDMA while conducting experiments with methylenedioxy-substituted compounds but did not test the psychoactivity of the compound.
Around 1975, Shulgin heard about the effects of Buy Ecstasy Online from a student. After hearing several more stories about the self-administration of MDMA, he decided to experiment with it. Shulgin was impressed with the effects of the substance and thought it could have therapeutic applications. Shulgin advertised the substance to therapists and psychiatrists for medical use, and it eventually became quite popular in the medical world for the treatment of various psychiatric disorders. During this time, the psychotherapist Dr. Leo Zeff came out of retirement and subsequently introduced the then-legal MDMA to over 4,000 patients. Then known as “Adam”, from the mid-1970s to the mid-1980s there was a growth of clinicians using MDMA around California.
The recreational use of Buy Ecstasy Online became popular at around the same time, particularly in nightclubs, and eventually caught the attention of the Drug Enforcement Administration. After several hearings, a US Federal Administrative Law Judge recommended that MDMA should be made a Schedule III controlled substance so that it could be used in the medical field. Despite this, the director of the DEA overruled this and classified MDMA as a Schedule I controlled substance.
In the United Kingdom, the 1971 Misuse of Drugs Act, which had already been altered in 1977 to include all ring-substituted amphetamines like MDMA, was further amended in 1985 to refer specifically to Ecstasy, placing it in the Class A category.
MDMA, or 3,4-methylenedioxy-N-methylamphetamine, is a synthetic molecule of the substituted amphetamine class. Molecules of the amphetamine class all contain a phenethylamine core comprised of a phenyl ring bound to an amino (NH2) group through an ethyl chain, with an additional methyl substitution at Rα. In addition to this, MDMA contains a methyl substitution on RN, a feature it shares with methamphetamine. Critically, the MDMA molecule also contains substitutions at R3 and R4 of the phenyl ring with oxygen groups — these oxygen groups are incorporated into a methylenedioxy ring through a methylene bridge. MDMA shares this methylenedioxy ring with other entactogens and stimulants like MDA, MDEA and MDAI.
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